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Complex Regional Pain Syndrome (CRPS) affects an estimated 200,000 people in the United States each year, making it a significant yet often misunderstood condition. This chronic pain disorder can arise after an injury or trauma, leading to a range of debilitating symptoms that impact daily life.

At Grand Rapids Pain, our skilled specialists are committed to delivering exceptional care for conditions like CRPS, proudly serving communities throughout West Michigan. Led by Dr. Keith Javery and Dr. Girish Juneja, we deliver advanced, FDA-approved treatment options to help manage and alleviate chronic pain. If you or a loved one is struggling with CRPS, contact us today to schedule an appointment and take the first step toward relief.

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Now, let's explore the underlying causes, symptoms, and available treatment options for CRPS in more detail.

What is CRPS?

Complex Regional Pain Syndrome (CRPS) is a chronic pain disorder that affects one limb, typically following an injury, surgery, or trauma.

It is characterized by persistent, intense pain that is disproportionate to the initial injury and is often accompanied by sensory, autonomic, and motor dysfunction. CRPS is believed to result from abnormalities in the nervous system, leading to amplified pain signals, inflammation, and circulation issues.

Types of CRPS:

  • CRPS 1 (Reflex Sympathetic Dystrophy - RSD): Occurs without a confirmed nerve injury and is often triggered by minor injuries, fractures, or surgeries. It is the most common form of CRPS.
  • CRPS 2 (Causalgia): Develops after a confirmed nerve injury, such as direct trauma to a nerve. The pain follows the nerve pathway and is typically more localized than CRPS 1.

Both types share similar symptoms, including burning pain, temperature changes, skin discoloration, swelling, and mobility issues, which can progressively worsen without early intervention.

Signs and Symptoms of CRPS

CRPS presents a variety of symptoms that can vary in intensity and duration. While some patients experience mild discomfort, others suffer from severe, life-altering pain. Recognizing the symptoms early is crucial for effective treatment.

Aside from constant, burning, or throbbing pain, other common symptoms of CRPS include:

  • Swelling and Skin Texture Changes: The affected area may become swollen, take on a shiny appearance, and feel unusually warm or cool compared to the rest of the body. 
  • Skin Color Variations: Abnormal blood flow can cause the skin to shift between shades of red, purple, pale, or mottled. 
  • Sensitivity and Temperature Fluctuations: Heightened sensitivity to touch, temperature changes, or even gentle stimuli like clothing or a breeze is common. 
  • Muscle Weakness and Movement Challenges: Over time, CRPS can lead to muscle atrophy, stiffness, and difficulties in moving the affected limb. 
  • Changes in Nail and Hair Growth: Abnormalities in nail and hair growth, such as accelerated growth or excessive thinning, may develop in the affected area.

CRPS symptoms can change and intensify over time, often becoming more severe if not addressed promptly. In the early stages, symptoms may appear intermittently, but as the condition advances, pain and dysfunction tend to become more constant.

Early intervention is crucial, so if you or someone you care about is experiencing these symptoms, seeking help sooner rather than later can make all the difference.

Causes and Risk Factors of CRPS

While the exact cause of Complex Regional Pain Syndrome (CRPS) isn’t fully understood, it is believed to be triggered by an abnormal response of the nervous system following an injury or trauma. CRPS typically develops after:

  • Fractures, Sprains, or Soft Tissue Injuries: Even minor injuries can lead to an exaggerated pain response in some individuals.
  • Surgical Procedures: Some patients experience CRPS after surgery, particularly in the limbs.
  • Nerve Damage: Injuries that impact the nerves, such as cuts, burns, or crush injuries, can disrupt pain signaling and lead to CRPS.
  • Immobilization: Extended periods of inactivity (e.g., wearing a cast) can contribute to CRPS development.

Certain factors may increase the likelihood of developing CRPS, including:

  • Being female (women are more commonly affected)
  • A history of migraines or other chronic pain conditions
  • Having a hyperactive immune system response
  • Psychological stress, anxiety, or depression

While CRPS can happen to anyone, early intervention is crucial in managing symptoms and preventing long-term disability. In the next section, we’ll explore the advanced treatment options available at Grand Rapids Pain.

Treatment Options for CRPS 1 & 2 at Grand Rapids Pain

At Grand Rapids Pain, we specialize in advanced interventional pain management, offering cutting-edge treatments for CRPS 1 & 2.  Our goal is to provide long-lasting relief for patients struggling with chronic nerve pain, particularly when conventional treatments have failed.

Peripheral Nerve Stimulation (PNS)

Peripheral Nerve Stimulation is a minimally invasive procedure that delivers mild electrical pulses to targeted nerves, interrupting pain signals before they reach the brain.

GRP offers a short-term trial to assess effectiveness—if the patient experiences at least 50% pain relief, a permanent device is implanted for long-term pain management.

Spinal Cord Stimulation (SCS)

Spinal Cord Stimulation is a well-established treatment for chronic nerve pain conditions like CRPS.

This therapy involves implanting a small device that sends electrical impulses to the spinal cord, effectively blocking pain signals.

Like PNS, SCS begins with a trial phase, ensuring that the patient experiences significant relief before permanent implantation.

Sympathetic Nerve Blocks

For patients with CRPS-related nerve dysfunction and pain, sympathetic nerve blocks can provide significant but temporary relief, often as part of a comprehensive treatment plan.

These injections target the sympathetic nervous system, reducing pain and improving mobility. Many patients experience progressive relief after a series of injections.

Medication Management for CRPS

At GRP, we use evidence-based medication strategies tailored to CRPS-specific nerve pain. Unlike general pain clinics, we focus on neuropathic pain relief, using medications such as:

  • Nerve pain modulators (e.g., gabapentin, pregabalin)
  • Topical anesthetics (e.g., lidocaine patches)
  • Selective muscle relaxants for targeted symptom control.

We carefully monitor medication plans to minimize side effects while maximizing relief for patients with treatment-resistant CRPS.

Minimally Invasive Spinal Techniques for CRPS

MIST 2.0 is an advanced, minimally invasive approach designed to target chronic pain at the source while reducing surgical risks These advanced procedures are designed to help patients with treatment-resistant CRPS regain function and improve their quality of life.

Some of the techniques we offer include:

  • Dorsal Root Ganglion (DRG) Stimulation: A specialized neuromodulation therapy that targets nerve clusters responsible for CRPS, providing precise and lasting relief. 
  • Advanced Epidural Injections: Delivers anti-inflammatory medication precisely to affected nerves, reducing swelling and pain with enhanced accuracy.

These minimally invasive techniques help reduce recovery time, lower complication risks, and provide long-lasting pain relief compared to traditional surgical interventions.

Importance of Early Diagnosis and Treatment

'If CRPS is suspected, early intervention by a board-certified pain specialist is critical. Research consistently shows that prompt diagnosis and treatment improve long-term outcomes and significantly lower the risk of disability. Patients who receive specialized care sooner experience better pain control and functional recovery.

At Grand Rapids Pain, we are committed to providing cutting-edge, patient-centered care for individuals suffering from CRPS. If you or a loved one is experiencing chronic nerve pain, schedule an appointment today to explore effective treatment options.

Why Choose Grand Rapids Pain for CRPS Treatment?

At Grand Rapids Pain, we specialize in advanced interventional pain management, offering FDA-approved treatments for CRPS 1 & 2. Led by Dr. Javery and Dr. Juneja, our team provides personalized, cutting-edge care to help patients regain mobility and improve their quality of life.

Why many patients trust Grand Rapids Pain:

  • Expert Pain Specialists: Dr. Javery and Dr. Juneja are board-certified leaders in chronic pain management.
  • Advanced Treatment Options: We offer Peripheral Nerve Stimulation (PNS), Spinal Cord Stimulation (SCS), and Minimally Invasive Spinal Techniques (MIST 2.0) for long-term relief.
  • Personalized Care Plans: Each treatment is tailored to your unique pain condition and recovery goals.
  • FDA-Approved Therapies: We use only evidence-based, clinically proven pain management solutions.
  • Compassionate, Patient-Focused Care: We prioritize your comfort, function, and long-term well-being.

Regain Control Over Your CRPS with GRP 

Living with CRPS can be challenging, but targeted treatments like nerve blocks and personalized medication plans can offer significant relief and improved quality of life. GRP specializes in providing compassionate, expert care tailored to your needs. 

Start your path to relief today by scheduling an appointment with GRP. Dr. Javery and Dr. Juneja are here to help you manage CRPS effectively and reclaim your mobility and well-being.

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